What Is the Clinical Relevance of the Discordance Between Fractional Flow Reserve and Coronary Flow Reserve?

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Clinical Relevance of Coronary Fractional Flow Reserve: Art-of-state

OBJECTIVE The objective was to delineate the current knowledge of fractional flow reserve (FFR) in terms of definition, features, clinical applications, and pitfalls of measurement of FFR. DATA SOURCES We searched database for primary studies published in English. The database of National Library of Medicine (NLM), MEDLINE, and PubMed up to July 2014 was used to conduct a search using the key...

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Is discordance of coronary flow reserve and fractional flow reserve due to methodology or clinically relevant coronary pathophysiology?

OBJECTIVES The purpose of this study was to determine whether observed discordance between coronary flow reserve (CFR) and fractional flow reserve (FFR) is due to methodology or reflects basic coronary pathophysiology. BACKGROUND Despite the clinical importance of coronary physiological assessment, relationships between its 2 most common tools, CFR and FFR, remain poorly defined. METHODS Th...

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Physiological basis and long-term clinical outcome of discordance between fractional flow reserve and coronary flow velocity reserve in coronary stenoses of intermediate severity.

BACKGROUND Discordance between fractional flow reserve (FFR) and coronary flow velocity reserve (CFVR) may reflect important coronary pathophysiology but usually remains unnoticed in clinical practice. We evaluated the physiological basis and clinical outcome associated with FFR/CFVR discordance. METHODS AND RESULTS We studied 157 intermediate coronary stenoses in 157 patients, evaluated by F...

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The relationship between coronary artery distensibility and fractional flow reserve

Discordance between angiography-based anatomical assessment of coronary stenosis severity and fractional flow reserve (FFR) has been attributed to several factors including lesion length and irregularity, and the myocardial territory supplied by the target vessel. We sought to examine if coronary arterial distensibility is an independent contributor to this discordance. There were two parts to ...

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Fractional flow reserve and complex coronary intervention.

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ژورنال

عنوان ژورنال: JACC: Cardiovascular Interventions

سال: 2017

ISSN: 1936-8798

DOI: 10.1016/j.jcin.2017.03.038